Little relatively unknown fact, if you have an id attribute on an element, you can reference it in this way:
// html
<button id="yo">…</button>
// js
yo.onclick = ...
Furthermore, child elements with a name attribute can be referenced in this way:
// html
<form id="x">
<input name="em">
</form>
// js
x.em.onclick = ...
Maybe not your favorite API, but it’s a thing.